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1

Targeting pattern-recognition receptors to discover new small molecule immune modulators

Zhu, Gengzheng, Xu, Yao, Cen, Xiaohong, Nandakumar, Kutty Selva, Liu, Shuwen, Cheng, Kui

Journal:

European Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 2.65 MB

english, 2018

2

Analysis of data from breast diseases treated with 5-alpha reductase inhibitors for benign prostatic hyperplasia

Fang, Qinghua, Chen, Peiya, Du, Ningchao, Nandakumar, Kutty Selva

Journal:

Clinical Breast Cancer

Year:

2019

Language:

english

File:

PDF, 10.67 MB

english, 2019

3

Emerging and state of the art hemagglutinin-targeted influenza virus inhibitors.

Zhang, Qiao, Liang, Taizhen, Nandakumar, Kutty Selva, Liu, Shuwen

Journal:

Expert Opinion on Pharmacotherapy

Year:

2020

File:

PDF, 1.23 MB

2020

4

IL-4-deficient mice develop less acute but more chronic relapsing collagen-induced arthritis

Lars Svensson, Kutty Selva Nandakumar, Åsa Johansson, Liselotte Jansson, Rikard Holmdahl

Journal:

European Journal of Immunology

Year:

2002

Language:

english

File:

PDF, 307 KB

english, 2002

5

Epitope-specific recognition of type II collagen by rheumatoid arthritis antibodies is shared with recognition by antibodies that are arthritogenic in collagen-induced arthritis in the mouse

Harald Burkhardt, Tobias Koller, Åke Engström, Kutty Selva Nandakumar, Javier Turnay, Hans G. Kraetsch, Joachim R. Kalden, Rikard Holmdahl

Journal:

Arthritis & Rheumatism

Year:

2002

Language:

english

File:

PDF, 491 KB

english, 2002

6

Antileukoproteinase: Modulation of neutrophil function and therapeutic effects on anti–type II collagen antibody–induced arthritis

Bettina Sehnert, Andrea Cavcic, Beate Böhm, Joachim R. Kalden, Kutty Selva Nandakumar, Rikard Holmdahl, Harald Burkhardt

Journal:

Arthritis & Rheumatism

Year:

2004

Language:

english

File:

PDF, 536 KB

english, 2004

7

Arthritogenic anti–type II collagen antibodies are pathogenic for cartilage-derived chondrocytes independent of inflammatory cells

S. Fatemah Amirahmadi, Senga Whittingham, Duncan E. Crombie, Kutty Selva Nandakumar, Rikard Holmdahl, Ian R. Mackay, Marie-Paule van Damme, Merrill J. Rowley

Journal:

Arthritis & Rheumatism

Year:

2005

Language:

english

File:

PDF, 647 KB

english, 2005

8

Blocking of experimental arthritis by cleavage of IgG antibodies in vivo

Kutty Selva Nandakumar, Björn P. Johansson, Lars Björck, Rikard Holmdahl

Journal:

Arthritis & Rheumatism

Year:

2007

Language:

english

File:

PDF, 161 KB

english, 2007

9

Arthritogenic antibodies specific for a major type II collagen triple-helical epitope bind and destabilize cartilage independent of inflammation

Kutty Selva Nandakumar, Estelle Bajtner, Leigh Hill, Beate Böhm, Merrill J. Rowley, Harald Burkhardt, Rikard Holmdahl

Journal:

Arthritis & Rheumatism

Year:

2008

Language:

english

File:

PDF, 849 KB

english, 2008

10

Cartilage oligomeric matrix protein induction of chronic arthritis in mice

Stefan Carlsen, Kutty Selva Nandakumar, Johan Bäcklund, Jens Holmberg, Malin Hultqvist, Mikael Vestberg, Rikard Holmdahl

Journal:

Arthritis & Rheumatism

Year:

2008

Language:

english

File:

PDF, 207 KB

english, 2008

11

Specific antibody protection of the extracellular cartilage matrix against collagen antibody–induced damage

Allyson M. Croxford, Duncan Crombie, Donald McNaughton, Rikard Holmdahl, Kutty Selva Nandakumar, Merrill J. Rowley

Journal:

Arthritis & Rheumatism

Year:

2010

Language:

english

File:

PDF, 312 KB

english, 2010

12

Integrated bioprocess for the production and isolation of urokinase from animal cell culture using supermacroporous cryogel matrices

Ashok Kumar, Vibha Bansal, Kutty Selva Nandakumar, Igor Yu. Galaev, Pradip K. Roychoudhury, Rikard Holmdahl, Bo Mattiasson

Journal:

Biotechnology and Bioengineering

Year:

2006

Language:

english

File:

PDF, 276 KB

english, 2006

13

Three-dimensional culture for monoclonal antibody production by hybridoma cells immobilized in macroporous gel particles

Suthasinee Nilsang, Vishal Nehru, Fatima M. Plieva, Kutty Selva Nandakumar, Sudip Kumar Rakshit, Rikard Holmdahl, Bo Mattiasson, Ashok Kumar

Journal:

Biotechnology Progress

Year:

2008

Language:

english

File:

PDF, 371 KB

english, 2008

14

Induction of arthritis by single monoclonal IgG anti-collagen type II antibodies and enhancement of arthritis in mice lacking inhibitory FcγRIIB

Kutty Selva Nandakumar, Maria Andrén, Pernilla Martinsson, Estelle Bajtner, Silvia Hellström, Rikard Holmdahl, Sandra Kleinau

Journal:

European Journal of Immunology

Year:

2003

Language:

english

File:

PDF, 239 KB

english, 2003

15

A genetic contamination in MHC-congenic mouse strains reveals a locus on chromosome 10 that determines autoimmunity and arthritis susceptibility

Kutty Selva Nandakumar, Rikard Holmdahl

Journal:

European Journal of Immunology

Year:

2005

Language:

english

File:

PDF, 319 KB

english, 2005

16

Arthritis induced with cartilage-specific antibodiesis IL-4-dependent

Kutty Selva Nandakumar, Rikard Holmdahl

Journal:

European Journal of Immunology

Year:

2006

Language:

english

File:

PDF, 427 KB

english, 2006

17

Endoglycosidase treatment abrogates IgG arthritogenicity: Importance of IgG glycosylation in arthritis

Kutty Selva Nandakumar, Mattias Collin, Arne Olsén, Falk Nimmerjahn, Anna M. Blom, Jeffrey V. Ravetch, Rikard Holmdahl

Journal:

European Journal of Immunology

Year:

2007

Language:

english

File:

PDF, 312 KB

english, 2007

18

Affinity binding of cells to cryogel adsorbents with immobilized specific ligands: effect of ligand coupling and matrix architecture

Ashok Kumar, Arancha Rodríguez-Caballero, Fatima M. Plieva, Igor Yu Galaev, Kutty Selva Nandakumar, Masamichi Kamihira, Rikard Holmdahl, Alberto Orfao, Bo Mattiasson

Journal:

Journal of Molecular Recognition

Year:

2005

Language:

english

File:

PDF, 304 KB

english, 2005

19

Pathogenic antibody recognition of cartilage

Kutty Selva Nandakumar

Journal:

Cell and Tissue Research

Year:

2010

Language:

english

File:

PDF, 232 KB

english, 2010

20

The role of collagen antibodies in mediating arthritis

Merrill J. Rowley, Kutty Selva Nandakumar, Rikard Holmdahl

Journal:

Modern Rheumatology

Year:

2008

Language:

english

File:

PDF, 279 KB

english, 2008

21

Do “infectious” prey select for high levels of natural antibodies in tropical pythons?

Thomas Madsen, Beata Ujvari, Kutty Selva Nandakumar, Dennis Hasselquist, Rikard Holmdahl

Journal:

Evolutionary Ecology

Year:

2007

Language:

english

File:

PDF, 259 KB

english, 2007

22

Antibodies to citrullinated proteins: molecular interactions and arthritogenicity

Hüseyin Uysal, Kutty Selva Nandakumar, Christoph Kessel, Sabrina Haag, Stefan Carlsen, Harald Burkhardt, Rikard Holmdahl

Journal:

Immunological Reviews

Year:

2010

Language:

english

File:

PDF, 690 KB

english, 2010

23

Monoclonal Antibody Production Using a New Supermacroporous Cryogel Bioreactor

Suthasinee Nilsang, Kutty Selva Nandakumar, Igor Yu. Galaev, Sudip Kumar Rakshit, Rikard Holmdahl, Bo Mattiasson, Ashok Kumar

Journal:

Biotechnology Progress

Year:

2007

Language:

english

File:

PDF, 387 KB

english, 2007

24

In vivo imaging of reactive oxygen and nitrogen species in inflammation using the luminescent probe L-012

Anders Kielland, Thomas Blom, Kutty Selva Nandakumar, Rikard Holmdahl, Rune Blomhoff, Harald Carlsen

Journal:

Free Radical Biology and Medicine

Year:

2009

Language:

english

File:

PDF, 771 KB

english, 2009

25

An encephalomyelitis-specific locus on chromosome 16 in mouse controls disease development and expression of immune-regulatory genes

Therese Lindvall, Kutty Selva Nandakumar, Kimia Yousefi, Rikard Holmdahl, Åsa Andersson

Journal:

Journal of Neuroimmunology

Year:

2011

Language:

english

File:

PDF, 833 KB

english, 2011

26

Evaluation of the Percentage of Peripheral T Cells with Two Different T Cell Receptor α-Chains and of their Potential Role in Autoimmunity

Alexandre Corthay, Kutty Selva Nandakumar, Rikard Holmdahl

Journal:

Journal of Autoimmunity

Year:

2001

Language:

english

File:

PDF, 129 KB

english, 2001

27

Collagen Type II and a Thermo-Responsive Polymer of N-Isopropylacrylamide Induce Arthritis Independent of Toll-Like Receptors: A Strong Influence by Major Histocompatibility Complex Class II and Ncf1 Genes

Akhilesh Kumar Shakya, Ashok Kumar, Dorota Klaczkowska, Malin Hultqvist, Kristin Hagenow, Rikard Holmdahl, Kutty Selva Nandakumar

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 2.33 MB

english, 2011

28

Enhancement of Antibody-Induced Arthritis via Toll-Like Receptor 2 Stimulation Is Regulated by Granulocyte Reactive Oxygen Species

Tiina Kelkka, Malin Hultqvist, Kutty Selva Nandakumar, Rikard Holmdahl

Journal:

The American Journal of Pathology

Year:

2012

Language:

english

File:

PDF, 1.35 MB

english, 2012

29

Role of anti-hinge antibodies in therapeutic cleavage of IgG: response to Drs. Lutz and Fumia

Kutty Selva Nandakumar, Rikard Holmdahl

Journal:

Trends in Immunology

Year:

2008

Language:

english

File:

PDF, 61 KB

english, 2008

30

Therapeutic cleavage of IgG: new avenues for treating inflammation

Kutty Selva Nandakumar, Rikard Holmdahl

Journal:

Trends in Immunology

Year:

2008

Language:

english

File:

PDF, 643 KB

english, 2008

31

Two monoclonal antibodies to precisely the same epitope of type II collagen select non-crossreactive phage clones by phage display: implications for autoimmunity and molecular mimicry

Yuekang Xu, Paul A. Ramsland, Janet M. Davies, Marita Scealy, Kutty Selva Nandakumar, Rikard Holmdahl, Merrill J. Rowley

Journal:

Molecular Immunology

Year:

2004

Language:

english

File:

PDF, 154 KB

english, 2004

32

The Plasminogen Activator/Plasmin System Is Essential for Development of the Joint Inflammatory Phase of Collagen Type II-Induced Arthritis

Jinan Li, Annelii Ny, Göran Leonardsson, Kutty Selva Nandakumar, Rikard Holmdahl, Tor Ny

Journal:

The American Journal of Pathology

Year:

2005

Language:

english

File:

PDF, 1.32 MB

english, 2005

33

Collagen Type II-Specific Monoclonal Antibody-Induced Arthritis in Mice: Description of the Disease and the Influence of Age, Sex, and Genes

Kutty Selva Nandakumar, Lars Svensson, Rikard Holmdahl

Journal:

The American Journal of Pathology

Year:

2003

Language:

english

File:

PDF, 673 KB

english, 2003

34

Efficient promotion of collagen antibody induced arthritis (CAIA) using four monoclonal antibodies specific for the major epitopes recognized in both collagen induced arthritis and rheumatoid arthritis

Kutty Selva Nandakumar, Rikard Holmdahl

Journal:

Journal of Immunological Methods

Year:

2005

Language:

english

File:

PDF, 405 KB

english, 2005

35

Pain mechanisms in animal models of rheumatoid arthritis

Christina Christianson, Duygu BalkisBas, Rikard Holmdahl, Nandakumar Kutty Selva, Tony Yaksh, Maripat Corr, Gary Firestein, Camilla I. Svensson

Journal:

Scandinavian Journal of Pain

Year:

2010

Language:

english

File:

PDF, 55 KB

english, 2010

36

Cartilage oligomeric matrix protein specific antibodies are pathogenic

Hui Geng, Kutty Selva Nandakumar, Anna Pramhed…

Journal:

Arthritis Research & Therapy

Year:

2012

Language:

english

File:

PDF, 1.07 MB

english, 2012

37

Cartilage oligomeric matrix protein deficiency promotes early onset and the chronic development of collagen-induced arthritis

Hui Geng, Stefan Carlsen, Kutty Selva Nandakumar…

Journal:

Arthritis Research & Therapy

Year:

2008

Language:

english

File:

PDF, 583 KB

english, 2008

38

Antibody-induced arthritis: disease mechanisms and genes involved at the effector phase of arthritis

Kutty Selva Nandakumar, Rikard Holmdahl

Journal:

Arthritis Research & Therapy

Year:

2006

Language:

english

File:

PDF, 1.06 MB

english, 2006

39

Type IX collagen deficiency enhances the binding of cartilage-specific antibodies and arthritis severity

Stefan Carlsen, Kutty Selva Nandakumar, Rikard Holmdahl

Journal:

Arthritis Research & Therapy

Year:

2006

Language:

english

File:

PDF, 619 KB

english, 2006

40

Collagen type II (CII)-specific antibodies induce arthritis in the absence of T or B cells but the arthritis progression is enhanced by CII-reactive T cells

Kutty Selva Nandakumar, Johan Bäcklund, Mikael Vestberg…

Journal:

Arthritis Research & Therapy

Year:

2004

Language:

english

File:

PDF, 281 KB

english, 2004

41

Incomplete B Cell Tolerance to Cartilage Oligomeric Matrix Protein in Mice

Geng, Hui, Nandakumar, Kutty Selva, Xiong, Li, Jie, Rui, Dong, Jiahui, Holmdahl, Rikard

Journal:

Arthritis & Rheumatism

Year:

2013

Language:

english

File:

PDF, 591 KB

english, 2013

42

Characterization of chemically defined poly-N-isopropylacrylamide based copolymeric adjuvants

Shakya, Akhilesh Kumar, Holmdahl, Rikard, Nandakumar, Kutty Selva, Kumar, Ashok

Journal:

Year:

2013

Language:

english

File:

PDF, 2.74 MB

english, 2013

43

Nerve Conduction Velocity Is Regulated by the Inositol Polyphosphate-4-Phosphatase II Gene

Lemcke, Susanne, Müller, Susen, Möller, Steffen, Schillert, Arne, Ziegler, Andreas, Cepok-Kauffeld, Sabine, Comabella, Manuel, Montalban, Xavier, Rülicke, Thomas, Nandakumar, Kutty Selva, Hemmer, Bern

Journal:

The American Journal of Pathology

Year:

2014

Language:

english

File:

PDF, 1.04 MB

english, 2014

44

Polymeric cryogels are biocompatible, and their biodegradation is independent of oxidative radicals

Shakya, Akhilesh Kumar, Holmdahl, Rikard, Nandakumar, Kutty Selva, Kumar, Ashok

Journal:

Journal of Biomedical Materials Research Part A

Year:

2014

Language:

english

File:

PDF, 1001 KB

english, 2014

45

Chemical cross-linking abrogates adjuvant potential of natural polymers

Shakya, Akhilesh Kumar, Kumar, Ashok, Nandakumar, Kutty Selva

Journal:

Year:

2014

Language:

english

File:

PDF, 506 KB

english, 2014

46

Keratinocyte growth factor (KGF) delays the onset of collagen-induced arthritis

Yakimchuk, Konstantin, Nandakumar, Kutty Selva, Chen, Liying, Holmdahl, Rikard, Okret, Sam, Jondal, Mikael

Journal:

Year:

2012

Language:

english

File:

PDF, 366 KB

english, 2012

47

The role of collagen antibodies in mediating arthritis

Rowley, Merrill J., Nandakumar, Kutty Selva, Holmdahl, Rikard

Journal:

Modern Rheumatology

Year:

2008

Language:

english

File:

PDF, 329 KB

english, 2008

48

Type II collagen-specific antibodies induce cartilage damage in mice independent of inflammation

Croxford, Allyson M., Whittingham, Senga, McNaughton, Donald, Nandakumar, Kutty Selva, Holmdahl, Rikard, Rowley, Merrill J.

Journal:

Arthritis & Rheumatism

Year:

2013

Language:

english

File:

PDF, 301 KB

english, 2013

49

Reactive Oxygen Species in Psoriasis and Psoriasis Arthritis: Relevance to Human Disease

Khmaladze, Ia, Nandakumar, Kutty Selva, Holmdahl, Rikard

Journal:

International Archives of Allergy and Immunology

Year:

2015

Language:

english

File:

PDF, 331 KB

english, 2015

50

Autoantibodies to citrullinated proteins induce joint pain independent of inflammation via a chemokine-dependent mechanism

Wigerblad, Gustaf, Bas, Duygu B, Fernades-Cerqueira, Cátia, Krishnamurthy, Akilan, Nandakumar, Kutty Selva, Rogoz, Katarzyna, Kato, Jungo, Sandor, Katalin, Su, Jie, Jimenez–Andrade, Juan Miguel, Finn,

Journal:

Annals of the Rheumatic Diseases

Year:

2015

Language:

english

File:

PDF, 3.90 MB

english, 2015

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